Hydrogen peroxide
Intervention4 papers1 finding
- Animals2
- Cells2
Outcomes
1Cellular senescence
upin human cells1
1 study
Cellular senescence
upin human cells1
Hydrogen peroxide induces cellular senescence in human cells.
“H 2 O 2 increased senescence-associated β-galactosidase positivity, TNFA expression, p16 and p21 abundance, and NF-κB phosphorylation.”
Cells50 μM for 1 hTHP-1-derived macrophage50 μM1 h
Aqueous Extract of Buddleja globosa Modulates Oxidative Stress-Induced Senescence-Associated Responses in THP-1-Derived Macrophages · Pharmaceuticals (Basel, Switzerland) · 12 Sep 2026
Latest
4Loss of lncRNA H19 suppresses osteoblast differentiation under oxidative stress
Overexpressing the noncoding RNA restored bone healing in mice, separating impaired osteogenesis from the onset of cellular senescence.
Dietary CoQ10 improves megakaryocyte function and reduces platelet hyperreactivity in aging mice
The supplement boosted autophagy via COPS3, enhancing megakaryocyte maturation and polyploidization without altering baseline platelet counts.
Ergothioneine carbon dot nanozymes reduce intervertebral disc degeneration in an animal model
The antioxidant nanozymes scavenged reactive oxygen species and reduced mitochondrial damage to protect nucleus pulposus cells.