FIN-56
Intervention1 paper1 findingPubChem 118986699ChEBI 176419
- Animals1
Outcomes
1Efferocytosis
downin human cells1
1 study
Efferocytosis
downin human cells1
FIN-56 impairs efferocytosis in human cells.
CellsTHP-1-derived macrophages5 μM48 h
Rapamycin reduces ferroptotic stress and shrinks atherosclerotic plaques in mice · International immunopharmacology · 2 Oct 2026
Latest
1AnimalsmTOR & rapamycin
Rapamycin reduces ferroptotic stress and shrinks atherosclerotic plaques in mice
The mTOR inhibitor restored macrophage efferocytosis and mitochondrial function while lowering aortic lipid burden in high-fat-fed ApoE-deficient mice.