TGFB1
GeneHomo sapiens1 paperHGNC 11766NCBI Gene 7040Taxon 9606
Latest
3AnimalsCellular senescence
Syringin reduces cellular senescence and pulmonary fibrosis in mice and cell models
Computational screening identified the natural compound, which interacts with CHK1 to blunt replication stress and fibrotic signaling.
AnimalsMitochondria
Parthenolide reduces senescence and skin fibrosis in scleroderma models
The compound targets Ero1L to stabilize contacts between mitochondria and the endoplasmic reticulum, mitigating tissue damage in cells and mice.