Nos3
GeneMus musculus1 paper2 findingsMGI 97362NCBI Gene 18127Taxon 10090
- Animals1
Interventions
1Intermittent fasting
upin mice1
1 study
Intermittent fasting
upin mice1
Intermittent fasting increases Nos3 in mice.
“ADF enhanced hepatocyte eNOS expression, and hepatocyte-specific eNOS knockout abolished the protective metabolic and anti-fibrotic effects of ADF.”
Animalsalternate-day fastinghepatocyte
Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Effects
1Liver fibrosis
is required forin mice1
1 study
Liver fibrosis
is required forin mice1
Nos3 is required for liver fibrosis in mice.
“ADF enhanced hepatocyte eNOS expression, and hepatocyte-specific eNOS knockout abolished the protective metabolic and anti-fibrotic effects of ADF.”
Animalsfor alternate-day fasting-mediated protectionhepatocyte
Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1AnimalsDietary restriction
Alternate-day fasting resolves liver fibrosis via hepatocyte eNOS signaling
Nitric oxide produced by hepatocytes during fasting blocks autophagy in stellate cells to halt fibrotic progression in mice.