Ccl2
GeneMus musculus1 paper2 findingsMGI 98259NCBI Gene 20296Taxon 10090
- Animals1
Interventions
1CTNNB1 deletion
downin mice1−79% to −58%
1 study
CTNNB1 deletion
downin mice1−79% to −58%
CTNNB1 deletion decreases Ccl2 in mice (-79%).
AnimalsAcanCreERT2-mediatedAcanCreERT2-mediatedintervertebral discfemales
Deleting beta-catenin in mouse disc cells lowers inflammation and immune cell recruitment · Aging cell · 1 Oct 2026
CTNNB1 deletion decreases Ccl2 in mice (-58%).
AnimalsAcanCreERT2-mediatedAcanCreERT2-mediatedintervertebral discmales
Deleting beta-catenin in mouse disc cells lowers inflammation and immune cell recruitment · Aging cell · 1 Oct 2026
Latest
1AnimalsInflammaging
Deleting beta-catenin in mouse disc cells lowers inflammation and immune cell recruitment
Simulating age-related declines in disc Wnt signaling blunted chemotactic gene expression and cut injury-induced myeloid infiltration roughly in half.