Temporomandibular joint osteoarthritis

Disease1 paper1 finding

Animals1

Interventions

1

Secukinumab

downin mice1

1 study

Secukinumab protects against temporomandibular joint osteoarthritis in mice.
Animalsunilateral anterior crossbite modelanti-IL-17A monoclonal antibody
Interleukin-17A drives joint chondrocyte senescence through mitochondrial dysfunction in mice · Oral diseases · 30 Sep 2026

Secukinumab →

Latest

1

AnimalsCellular senescence1 Oct

Interleukin-17A drives joint chondrocyte senescence through mitochondrial dysfunction in mice

Blocking the cytokine with secukinumab reduced cartilage senescence and slowed osteoarthritis progression in a mouse model.

Oral Diseases · Zhu M et al.