Exosomes

Biomarker1 paper

Latest

8

Crosstalk between exosomes and cellular senescence: A core vicious loop promoting α-synuclein pathology in Parkinson's disease

ReviewNeural Regeneration Research

Yesterday

Clinical Translation of Mesenchymal Stem Cells to Medicinal Signaling Cells: Origins, Clinical Applications, and the Future of Regenerative Medicine-2026 Arnold I. Caplan Award for Distinguished Research in Orthobiologics

ReviewThe Journal of the American Academy of Orthopaedic Surgeons

1 Oct

AnimalsCellular senescence30 Sep

Engineered exosome-mimetic nanoparticles improve liver function in aged mice

The synthetic particles deliver microRNAs and proteins to reduce senescence, lower fibrosis, and shift macrophages toward a pro-resolving state.

Biomaterials Advances · Zhang L et al.

AnimalsCellular senescence28 Sep

Bone-targeted exosomes delivering betaine reverse bone loss in osteoporotic rats

The engineered delivery vehicle enhances autophagy in senescent stem cells and suppresses osteoclast activity to restore bone metabolic homeostasis.

Advanced Materials · Li X et al.

Endocrine and Molecular Mechanisms of Oocyte Aging: From Gonadotropin Signaling to Metabolic and Microenvironmental Dysfunction

ReviewCurrent Issues in Molecular Biology

26 Sep

Aging Biology of Bone-to-Tendon Healing and the Epigenetic Clock: A Biological-Age Readout of Rotator Cuff Healing Capacity

ReviewBiomedicines

26 Sep

AnimalsBrain aging26 Sep

Intranasal Arc-engineered exosomes reduce Alzheimer pathology by restoring autophagy

The targeted nanoplatform cleared amyloid deposits and suppressed neuroinflammation in an Alzheimer's model by inhibiting mTOR signaling.

Nanomedicine · Sun C et al.

Hyperglycaemia-induced molecular reprogramming of proximal tubular epithelial cells and its contribution to diabetic kidney disease progression-a narrative review

ReviewFrontiers in Cell and Developmental Biology

26 Sep