Aging clocksHumans29 Sep 2026

Plasma per- and polyfluoroalkyl substance (PFAS) concentrations in mid-childhood and associations with DNA methylation and epigenetic aging through early adolescence

Environmental Research

The paper

Smith A, Hernandez-Castro I, Bozack AK et al.

Environmental Research · 28 Sep 2026

doi.org/10.1016/j.envres.2026.125759 PubMed

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HumansPreprint29 Sep

Biological age uncertainty independently predicts mortality and health decline in humans

Researchers derived biological age uncertainty across UK Biobank participants, finding that higher uncertainty reflects reduced physiological coherence and predicts worse health outcomes.

medRxiv · Li Y et al.

HumansPreprint1 Oct

Organ age acceleration and mortality risk reflect distinct biological processes

Multi-omics clocks across fourteen organs reveal divergent molecular programs and uncover thirteen candidate genes separating age acceleration from mortality.

Research Square · Na R et al.

Humans26 Sep

Retinal imaging model predicts age and reveals sex differences in human aging

The retinal age gap correlates with mortality, disease risks, and sex-specific genetic pathways in more than 71,000 UK Biobank participants.

Nature Communications · Trofimova O et al.

HumansYesterday

Blood cell composition explains substantial variation in DNA methylation age

Cell counts explain less variation in age acceleration and only modestly affect its links to mortality and 176 incident health outcomes.

Genome Medicine · Jonkman TH et al.

Humans26 Sep

Kidney tubular epithelial cells drive accelerated epigenetic aging in disease

A cross-species single-cell atlas links injured human kidney cells and aged mouse kidneys to shared chromatin reorganization and impaired repair.

Nature Aging · Jeong H et al.

Plasma per- and polyfluoroalkyl substance (PFAS) concentrations in mid-childhood and associations with DNA methylation and epigenetic aging through early adolescence

The paper

More on Aging clocks

Biological age uncertainty independently predicts mortality and health decline in humans

Organ age acceleration and mortality risk reflect distinct biological processes

Retinal imaging model predicts age and reveals sex differences in human aging

Blood cell composition explains substantial variation in DNA methylation age

Kidney tubular epithelial cells drive accelerated epigenetic aging in disease