Oxidative Stress in Animals: A Systematic Analysis from Signaling Pathways to Biological Effects
Abstract · CC BY
Oxidative stress is caused by the imbalance between the generation of free reactive oxygen species (ROS)/reactive nitrogen species (RNS) and the antioxidant defense systems, which participate in animal growth, development, disease pathogenesis, and aging.
- Chronic inflammation
- Genomic instability
- Apoptosis
- DNA damage response
- MAPK/ERK signalling
- NF-κB signalling
- NRF2–KEAP1 antioxidant response
- Oxidative stress and ROS signalling
- PI3K–AKT signalling
The paper
Oxidative Stress in Animals: A Systematic Analysis from Signaling Pathways to Biological Effects
Chang L, Liu C, Huang G
Life · 11 Sep 2026