Cells26 Sep 2026

Drug-Induced Reduction in 80Q Aggregates in a Dictyostelium discoideum Model of PolyQ Disease

Biomedicines

Abstract · CC BY

Background/Objectives : Polyglutamine (polyQ) expansion induces protein misfolding, aggregation, and neurodegeneration; however, effective strategies for aggregate clearance remain limited.

The paper

Upadhyay B, Akhtar A, Rawat R et al.

Biomedicines · 28 Aug 2026

doi.org/10.3390/biomedicines14091931 PubMed

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Drug-Induced Reduction in 80Q Aggregates in a Dictyostelium discoideum Model of PolyQ Disease

The paper

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