MitochondriaAnimals
Impaired mitochondrial proteostasis underlies cardiomyocyte bioenergetic dysfunction in a murine 3-hit model of heart failure with preserved ejection fraction
- High-fat diet
- L-name
- Loss of proteostasis
- Mitochondrial dysfunction
- Mitochondrial biogenesis (PGC-1α)
- Oxidative phosphorylation
- Ubiquitin–proteasome system
- Diastolic dysfunction
- Heart failure with preserved ejection fraction
- Ubiquitinated mitochondrial proteins
- Mus musculus
The paper
Impaired mitochondrial proteostasis underlies cardiomyocyte bioenergetic dysfunction in a murine 3-hit model of heart failure with preserved ejection fraction
Li X, Fu Y, do Carmo JM et al.
American Journal of Physiology. Heart and Circulatory Physiology · 19 Sep 2026