Aging clocksHumans26 Sep 2026

Early-life nutritional deprivation and multimorbidity in middle- aged and older adults: a longitudinal exploratory mediation analysis of biological aging

Frontiers in Nutrition

Abstract · CC BY

Objective This study aimed to examine the longitudinal association between childhood food deprivation and physical-psychological-cognitive multimorbidity (PPC-MM), and to explore whether Light-BioAge mediates this association.

The paper

Wang Q, Ma L, Tian Z et al.

Frontiers in Nutrition · 10 Sep 2026

doi.org/10.3389/fnut.2026.1908542 PubMed

See all

HumansPreprint29 Sep

Biological age uncertainty independently predicts mortality and health decline in humans

Researchers derived biological age uncertainty across UK Biobank participants, finding that higher uncertainty reflects reduced physiological coherence and predicts worse health outcomes.

medRxiv · Li Y et al.

HumansPreprint1 Oct

Organ age acceleration and mortality risk reflect distinct biological processes

Multi-omics clocks across fourteen organs reveal divergent molecular programs and uncover thirteen candidate genes separating age acceleration from mortality.

Research Square · Na R et al.

Humans26 Sep

Retinal imaging model predicts age and reveals sex differences in human aging

The retinal age gap correlates with mortality, disease risks, and sex-specific genetic pathways in more than 71,000 UK Biobank participants.

Nature Communications · Trofimova O et al.

HumansYesterday

Blood cell composition explains substantial variation in DNA methylation age

Cell counts explain less variation in age acceleration and only modestly affect its links to mortality and 176 incident health outcomes.

Genome Medicine · Jonkman TH et al.

Humans26 Sep

Kidney tubular epithelial cells drive accelerated epigenetic aging in disease

A cross-species single-cell atlas links injured human kidney cells and aged mouse kidneys to shared chromatin reorganization and impaired repair.

Nature Aging · Jeong H et al.

Early-life nutritional deprivation and multimorbidity in middle- aged and older adults: a longitudinal exploratory mediation analysis of biological aging

The paper

More on Aging clocks

Biological age uncertainty independently predicts mortality and health decline in humans

Organ age acceleration and mortality risk reflect distinct biological processes

Retinal imaging model predicts age and reveals sex differences in human aging

Blood cell composition explains substantial variation in DNA methylation age

Kidney tubular epithelial cells drive accelerated epigenetic aging in disease