Tamoxifen
Intervention2 papers2 findingsPubChem 2733526ChEBI 41774
- Animals1
- Cells1
Outcomes
2Ovarian aging trajectories
no changein mice1
1 study
Ovarian aging trajectories
no changein mice1
Tamoxifen has no effect on ovarian aging trajectories in mice.
Animalslong-termovary12 monthsfemales
Tamoxifen causes temporary ovarian disruption without altering long-term mouse aging trajectories · bioRxiv : the preprint server for biology · 8 Sep 2026 · Preprint
Estrous cyclicity
downin mice1
1 study
Estrous cyclicity
downin mice1
Tamoxifen impairs estrous cyclicity in mice.
Animalsshortly after administrationovaryfemales
Tamoxifen causes temporary ovarian disruption without altering long-term mouse aging trajectories · bioRxiv : the preprint server for biology · 8 Sep 2026 · Preprint
Latest
2Tamoxifen causes temporary ovarian disruption without altering long-term mouse aging trajectories
A new preprint shows tamoxifen-inducible mouse models remain valid for ovarian aging research despite transient disruptions to estrous cycling.