Mtdna depletion
Intervention1 paper2 findings
- Cells1
Outcomes
2Phosphorylated tau
downin human cells1
1 study
Phosphorylated tau
downin human cells1
Mtdna depletion decreases phosphorylated tau in human cells.
Cellschronic mtDNA depletion (rho0)SH-SY5Y
Chronic mitochondrial DNA depletion alters MAPT splicing and increases tau levels · Journal of Alzheimer's disease : JAD · 29 Sep 2026
MAPT
upin human cells1
1 study
MAPT
upin human cells1
Mtdna depletion increases MAPT in human cells.
Cellschronic mtDNA depletion (rho0)SH-SY5Y
Chronic mitochondrial DNA depletion alters MAPT splicing and increases tau levels · Journal of Alzheimer's disease : JAD · 29 Sep 2026