GRTP1 knockout
Intervention1 paper1 finding
- Animals1
Outcomes
1Mitochondrial dysfunction
upin mice1
1 study
Mitochondrial dysfunction
upin mice1
GRTP1 knockout induces mitochondrial dysfunction in mice.
“Grtp1 ablation recapitulates aging phenotypes, including oxidative stress, mitochondrial dysfunction, impaired spermatogenesis, and offspring anxiety and social deficits.”
Animalsgermlinemales
Protein Grtp1 protects male germlines from aging and prevents offspring behavioral deficits · Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 27 Sep 2026
Latest
1Animals
Protein Grtp1 protects male germlines from aging and prevents offspring behavioral deficits
Growth hormone treatment rescues germline redox balance and sperm quality in aged males through a Grtp1-dependent mechanism.