Growth hormone
Intervention1 paperPubChem 170907453
- Animals1
Latest
3AnimalsBrain aging
Ghrelin alleviates aging-related cognitive impairment by restoring microglial autophagy
Researchers identified ghrelin as a key metabolic factor that reduces microglial senescence and inflammation through the SHBG/JNK1/Beclin1 signaling axis.
Animals
Protein Grtp1 protects male germlines from aging and prevents offspring behavioral deficits
Growth hormone treatment rescues germline redox balance and sperm quality in aged males through a Grtp1-dependent mechanism.
AnimalsMitochondria
Deleting liver growth hormone receptors accelerates aging phenotypes and shortens lifespan in mice
The loss of hepatic growth hormone signaling disrupts lipid metabolism and causes mitochondrial damage that can be counteracted by inhibiting PDK4.