FOXO3 overexpression
Intervention1 paper4 findings
- Animals1
Outcomes
4Cell proliferation
downin chicken cells1
1 study
Cell proliferation
downin chicken cells1
FOXO3 overexpression decreases cell proliferation in chicken cells.
Cellsprimordial germ cell
FOXO3 overexpression delays primordial follicle activation in chickens · Poultry science · 21 Sep 2026
Apoptosis
downin chickens1
1 study
Apoptosis
downin chickens1
FOXO3 overexpression decreases apoptosis in chickens.
Animalsat 3 dphovaryfemales
FOXO3 overexpression delays primordial follicle activation in chickens · Poultry science · 21 Sep 2026
PI3K–AKT signalling
downin chickens1
1 study
PI3K–AKT signalling
downin chickens1
FOXO3 overexpression inhibits PI3K–AKT signalling in chickens.
Animalsat 4 dphovaryfemales
FOXO3 overexpression delays primordial follicle activation in chickens · Poultry science · 21 Sep 2026
Primordial follicle activation
downin chickens1
1 study
Primordial follicle activation
downin chickens1
FOXO3 overexpression decreases primordial follicle activation in chickens.
Animalsin germline chimeric chickensovary21 daysfemales
FOXO3 overexpression delays primordial follicle activation in chickens · Poultry science · 21 Sep 2026
Latest
1FOXO3 overexpression delays primordial follicle activation in chickens
Overexpressing the transcription factor kept avian follicles dormant and suppressed PI3K and AKT signaling during early ovarian development.