Fenofibrate
Intervention1 paper3 findingsPubChem 3339ChEBI 5001
- Human trial1
Outcomes
3Monocyte
downin mice1
1 study
Monocyte
downin mice1
Fenofibrate decreases monocyte in mice.
Animalsin chronic traumatic brain injurybrain parenchyma
Cranial bone marrow monocytes drive brain injury inflammation and respond to fenofibrate · Science translational medicine · 30 Sep 2026
Cognitive function
upin humans1
1 study
Cognitive function
upin humans1
Fenofibrate improves cognitive function in humans.
Human trialin chronic traumatic brain injuryn = 40
Cranial bone marrow monocytes drive brain injury inflammation and respond to fenofibrate · Science translational medicine · 30 Sep 2026
NfL
downin humans1
1 study
NfL
downin humans1
Fenofibrate decreases NfL in humans.
Human trialin chronic traumatic brain injuryplasman = 40
Cranial bone marrow monocytes drive brain injury inflammation and respond to fenofibrate · Science translational medicine · 30 Sep 2026
Latest
1Cranial bone marrow monocytes drive brain injury inflammation and respond to fenofibrate
Targeting PPARα deficiency in cranial bone marrow monocytes improved cognitive function and reduced neurodegeneration markers in older patients with chronic brain injury.