Cinaciguat
Intervention1 paper4 findingsPubChem 9808022ChEBI 142433
- Animals1
Outcomes
4Ldlr
upin rats1
1 study
Ldlr
upin rats1
Cinaciguat increases Ldlr in rats.
Animalshepatocyte
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026
Hbegf
upin rats1
1 study
Hbegf
upin rats1
Cinaciguat increases Hbegf in rats.
Animalsliver sinusoidal endothelial cell
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026
LDL
downin rats1
1 study
LDL
downin rats1
Cinaciguat decreases LDL in rats.
Animalsblood
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026
Amyloid-beta 40
downin rats1
1 study
Amyloid-beta 40
downin rats1
Cinaciguat decreases amyloid-beta 40 in rats (halved).
Animalsblood
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026
Latest
1Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats
Cinaciguat reversed endothelial defenestration and restored paracrine signaling that enables rat hepatocytes to clear circulating lipids and amyloid-beta.