LDL

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Cinaciguat

downin rats1

1 study

Cinaciguat decreases LDL in rats.
Animalsblood
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026

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Animals28 Sep

Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats

Cinaciguat reversed endothelial defenestration and restored paracrine signaling that enables rat hepatocytes to clear circulating lipids and amyloid-beta.

The Journal of Biological Chemistry · de Leve SJ et al.