Ldlr
GeneRattus norvegicus1 paper1 findingNCBI Gene 300438Taxon 10116
- Animals1
Interventions
1Cinaciguat
upin rats1
1 study
Cinaciguat
upin rats1
Cinaciguat increases Ldlr in rats.
Animalshepatocyte
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats · The Journal of biological chemistry · 26 Sep 2026
Latest
1Animals
Activating soluble guanylate cyclase restores amyloid-beta and LDL clearance in aged rats
Cinaciguat reversed endothelial defenestration and restored paracrine signaling that enables rat hepatocytes to clear circulating lipids and amyloid-beta.