CD47 antibody
Intervention1 paper2 findings
- Animals1
Outcomes
2Cardiac dysfunction
downin mice1
1 study
Cardiac dysfunction
downin mice1
CD47 antibody decreases cardiac dysfunction in mice.
“and improved doxorubicin-induced cardiac dysfunction.”
Animalsdoxorubicin-inducedheartmales
CD47 blockade reduces doxorubicin-induced cardiac aging in male mice · Physiological reports · 1 Sep 2026
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
CD47 antibody decreases cellular senescence in mice.
“Blocking CD47 with a specific antibody attenuated doxorubicin-induced cardiac aging and cardiomyocyte senescence in vivo and in vitro”
Animalsdoxorubicin-inducedheartmales
CD47 blockade reduces doxorubicin-induced cardiac aging in male mice · Physiological reports · 1 Sep 2026
Latest
1AnimalsCellular senescence
CD47 blockade reduces doxorubicin-induced cardiac aging in male mice
Inhibiting CD47 lessens heart dysfunction and blunts cellular senescence caused by the chemotherapy drug doxorubicin.