Cd47
GeneMus musculus1 paper1 findingMGI 96617NCBI Gene 16423Taxon 10090
- Animals1
Interventions
1Doxorubicin
upin mice1
1 study
Doxorubicin
upin mice1
Doxorubicin increases Cd47 in mice.
“Doxorubicin increased p53, p16, and p21 expression in mouse hearts, accompanied by marked CD47 upregulation.”
Animalsheartmales
CD47 blockade reduces doxorubicin-induced cardiac aging in male mice · Physiological reports · 1 Sep 2026
Latest
1AnimalsCellular senescence
CD47 blockade reduces doxorubicin-induced cardiac aging in male mice
Inhibiting CD47 lessens heart dysfunction and blunts cellular senescence caused by the chemotherapy drug doxorubicin.