Arc-engineered exosomes
Intervention1 paper4 findings
- Animals1
Outcomes
4Autophagy
upin animals1
1 study
Autophagy
upin animals1
Arc-engineered exosomes activate autophagy.
Animalsneural stem cell-derived exosomes overexpressing Arc
Intranasal Arc-engineered exosomes reduce Alzheimer pathology by restoring autophagy · Nanomedicine : nanotechnology, biology, and medicine · 25 Sep 2026
mTOR signalling
downin animals1
1 study
mTOR signalling
downin animals1
Arc-engineered exosomes inhibit mTOR signalling.
Animalsneural stem cell-derived exosomes overexpressing Arc
Intranasal Arc-engineered exosomes reduce Alzheimer pathology by restoring autophagy · Nanomedicine : nanotechnology, biology, and medicine · 25 Sep 2026
Amyloid-beta
downin animals1
1 study
Amyloid-beta
downin animals1
Arc-engineered exosomes decrease amyloid-beta.
AnimalsAlzheimer's diseaseneural stem cell-derived exosomes overexpressing Arc
Intranasal Arc-engineered exosomes reduce Alzheimer pathology by restoring autophagy · Nanomedicine : nanotechnology, biology, and medicine · 25 Sep 2026
Cognitive deficits
upin animals1
1 study
Cognitive deficits
upin animals1
Arc-engineered exosomes improve cognitive deficits.
AnimalsAlzheimer's diseaseneural stem cell-derived exosomes overexpressing Arc
Intranasal Arc-engineered exosomes reduce Alzheimer pathology by restoring autophagy · Nanomedicine : nanotechnology, biology, and medicine · 25 Sep 2026
Latest
1Intranasal Arc-engineered exosomes reduce Alzheimer pathology by restoring autophagy
The targeted nanoplatform cleared amyloid deposits and suppressed neuroinflammation in an Alzheimer's model by inhibiting mTOR signaling.