Shbg
GeneMus musculus1 paper1 findingMGI 98295NCBI Gene 20415Taxon 10090
- Animals1
Interventions
1Ghrelin
downin mouse cells1
1 study
Ghrelin
downin mouse cells1
Ghrelin decreases Shbg in mouse cells.
“Sex hormone-binding globulin (SHBG) showed mainly cytoplasmic localization, was identified as a potential mediator of ghrelin signaling in microglia, and its expression was downregulated following ghrelin treatment.”
Cellsmicroglia
Ghrelin alleviates aging-related cognitive impairment by restoring microglial autophagy · Aging cell · 29 Sep 2026
Latest
1AnimalsBrain aging
Ghrelin alleviates aging-related cognitive impairment by restoring microglial autophagy
Researchers identified ghrelin as a key metabolic factor that reduces microglial senescence and inflammation through the SHBG/JNK1/Beclin1 signaling axis.