Postural Instability/Gait Difficulty
Disease1 paper1 finding
- Humans1
Associations
1SMPD1
upin humans1
1 study
SMPD1
upin humans1
SMPD1 is associated with Postural Instability/Gait Difficulty in humans.
Humans
Disrupted sphingolipid metabolism drives lysosomal and mitochondrial failure in Parkinson's disease · bioRxiv · 28 Sep 2026 · Preprint
Latest
1Disrupted sphingolipid metabolism drives lysosomal and mitochondrial failure in Parkinson's disease
A preprint shows SMPD1 upregulation collapses a sphingolipid salvage pathway, causing mitophagy defects and marking aggressive motor phenotypes.