Heart failure

Disease2 papers1 findingMeSH D006333

Humans1

Associations

Organ age gap

upin humans1

1 study

Organ age gap is associated with heart failure in humans.
Humansat baseline across HF severity
Proteomic multi-organ aging accelerates before adverse events in heart failure patients · European journal of heart failure · 25 Sep 2026

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Latest

Heart Failure: Lipid Metabolism Disorders Driving Cellular Senescence Through a Vicious Cycle, and Possible Intervention Strategies

ReviewFrontiers in Bioscience

30 Sep

AnimalsInflammaging29 Sep

Persistent interferon-gamma fuels chronic cardiac remodeling after heart attacks in aged mice

A conserved interferon-gamma signature and heightened T cell recruitment drive worse long-term heart failure outcomes in older mice following myocardial infarction.

Journal of Molecular and Cellular Cardiology · Melika ET et al.

Impaired mitochondrial proteostasis underlies cardiomyocyte bioenergetic dysfunction in a murine 3-hit model of heart failure with preserved ejection fraction

AnimalsAmerican Journal of Physiology. Heart and Circulatory Physiology

26 Sep

HumansAging clocks26 Sep

Proteomic multi-organ aging accelerates before adverse events in heart failure patients

Organ age gaps for the kidney, lung, and immune system predicted patient outcomes independently of standard clinical biomarkers.

European Journal of Heart Failure · Qu K et al.