IL-5

Biomarker2 papers1 finding

Associations

Chronic obstructive pulmonary disease

upin humans1

1 study

IL-5 is associated with chronic obstructive pulmonary disease in humans.
Humanshigh-risk individuals (COPD-SQ ≥ 16, preserved lung function)n = 89
Age-linked immune profiles identify distinct risk groups for chronic obstructive pulmonary disease · Journal of inflammation research · 22 Sep 2026

Inhibiting the PERK pathway lowered cellular senescence and inflammatory markers in mouse models and cultured human airway cells.

Inflammation Research · Huang YT et al.

Clustering four age-associated inflammatory cytokines separated adults into three distinct endotypes tied to early chronic lung disease risk.

Journal of Inflammation Research · Wu B et al.