From ClinicalTrials.gov

Clinical trials

Trials of drugs and interventions aimed at aging, of age-related conditions through aging biology, and of healthspan itself: new registrations, status changes and first results.

Phase 1RecruitingAge-related condition

PET Imaging of Phosphodiesterase-4 (PDE4) in Volunteers With Alzheimer Disease (AD) or Mild Cognitive Impairment (MCI)

18F-PF974, 18F-florbetaben in Alzheimer s Disease, Mild Cognitive Impairment, Healthy

National Institute of Mental Health (NIMH) · 90 planned · NCT07169630 · updated 2 Oct 2026

Phase 1Not yet recruitingAge-related condition

Registered · 2 Oct 2026

[11C]PS13 PET Imaging of Neuroinflammation in Heart Failure With Reduced Ejection Fraction (NEURO-HF)

[11C]PS13: [carbon-11]PS13; COX-1 PET radioligand, Sacubitril-Valsartan in Heart Failure With Reduced Ejection Fraction, Cognitive Impairment, Mild, Neuroinflammation

Stony Brook University · 18 planned · NCT07856043 · updated 2 Oct 2026

Phase 1Not yet recruitingAge-related condition

Registered · 2 Oct 2026

Safety and Preliminary Efficacy of Adipose-Derived Stem Cell Secretome in Frailty (VinVital)

VinVital in Frailty Syndrome, Aging

Vinmec Research Institute of Stem Cell and Gene Technology · 20 planned · NCT07856602 · updated 2 Oct 2026

Phase 1/2Not yet recruitingGeroscience intervention

Precision Microbiota Interventions for Senoreduction Trial (PreMIS)

Limosilactobacillus reuteri, Blueberry extract in HIV Infections, Alcohol Drinking, Aging

Louisiana State University Health Sciences Center in New Orleans · 160 planned · NCT07462767 · updated 1 Oct 2026

Early phase 1RecruitingGeroscience intervention

Medication Combinations of Dasatinib, Quercetin, Fisetin, Temozolomide, LMP744, and Autologous TLPO Vaccine for the Treatment of Previously Treated Glioma With Residual Disease (Senolytics)

Biospecimen Collection, Dasatinib, Fisetin in Glioma

Mayo Clinic · 30 planned · NCT07025226 · updated 1 Oct 2026