TrialPhase 1/2Not yet recruiting
Precision Microbiota Interventions for Senoreduction Trial (PreMIS)
Geroprotective Precision Medicine Strategies in PWH That Use Alcohol
- Sponsor
- Louisiana State University Health Sciences Center in New Orleans (Academic or other)
- Enrolment
- 160 planned
- Conditions
- HIV Infections; Alcohol Drinking; Aging; Immunosenescence
- Interventions
- Limosilactobacillus reuteri; Blueberry extract
- Ages
- adults, older adults
- Registry
- NCT07462767
From the registry
People with HIV who drink alcohol are at increased risk for accelerated aging biology, including increased immune senescence. This randomized, double-blind, crossover clinical trial evaluates two generally recognized as safe (GRAS) microbiota-targeted interventions on immune senescence biomarkers.
Primary outcomes
- Change in circulating senescent T cell numbers