More than the 'master regulator of cytosolic proteostasis': new roles for HSF1 in promoting tissue health
Labbadia J
Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences · 1 Oct 2026
The mTOR inhibitor restored macrophage efferocytosis and mitochondrial function while lowering aortic lipid burden in high-fat-fed ApoE-deficient mice.
The herbal formula delayed thymic involution, restored regulatory T cell function, and improved maternal-fetal immune tolerance by altering metabolic signaling in aging female mice.
Overexpressing the noncoding RNA restored bone healing in mice, separating impaired osteogenesis from the onset of cellular senescence.
Profiling conditioned media revealed that altered sphingolipid signaling reduces muscle stem cell pools in human cell cultures.
