Cellular senescenceCells28 Sep 2026

The Eukaryotic Host-Microbe-Phage-Nutrition Interplay Determines the Bacterial Effectors of Supplemental Lysine's Health Benefits: An Experimental Cellular Senescence Model of Digestive Conditions in Older Adults

Mechanisms of Ageing and Development

The paper

Ghadimi D, Blömer S, Kaya AŞ et al.

Mechanisms of Ageing and Development · 26 Sep 2026

doi.org/10.1016/j.mad.2026.112260 PubMed

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DNA methylation proxies of senescence markers track human disease and mortality

The new blood-based tools estimate senescence gene activity to predict incident diseases, all-cause mortality, and clinical treatment responses.

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A deep learning score for cellular senescence predicts human mortality and disease risk

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The Eukaryotic Host-Microbe-Phage-Nutrition Interplay Determines the Bacterial Effectors of Supplemental Lysine's Health Benefits: An Experimental Cellular Senescence Model of Digestive Conditions in Older Adults

The paper

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Dasatinib and quercetin reduce liver fibrosis in a phase-2 MASH trial

A distinct p21-driven macrophage senotype accumulates during aging and liver disease

DNA methylation proxies of senescence markers track human disease and mortality

Bispecific T cell engager eliminates senescent cells in mice and nonhuman primates

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