ULK1 knockdown + ULK2 knockdown
Intervention1 paper1 finding
- Animals1
Outcomes
1Skeletal muscle
upin mice1+13%
1 study
Skeletal muscle
upin mice1+13%
ULK1 knockdown + ULK2 knockdown induces skeletal muscle in mice (13%).
Animalsplasmid-encoded microRNA electroporationskeletal muscleup to 4 weeks
Loss of ULK1 and ULK2 drives muscle growth in mice but impairs force · bioRxiv : the preprint server for biology · 10 Sep 2026 · Preprint
Latest
1Loss of ULK1 and ULK2 drives muscle growth in mice but impairs force
While lifelong depletion reduced muscle strength, short-term deficiency in adult mice induced hypertrophy without degrading muscle quality or contractile performance.