RNA polymerase ii inhibition
Intervention1 paper2 findings
- Model organisms1
Outcomes
1Growth
upin human cells1upin worms1
1 study
Growth
upin human cells1upin worms1
RNA polymerase ii inhibition improves growth in human cells.
CellsHP1-deficient cells
Innate immune stress activation drives pathology caused by heterochromatin loss · bioRxiv · 26 Sep 2026 · Preprint
RNA polymerase ii inhibition improves growth in worms.
Model organismsHP1 mutant background
Innate immune stress activation drives pathology caused by heterochromatin loss · bioRxiv · 26 Sep 2026 · Preprint
Latest
1Model organismsPreprint
Innate immune stress activation drives pathology caused by heterochromatin loss
Researchers found that dampening RNA polymerase II activity relieved growth defects triggered by heterochromatin disruption in worms and human cells.