PLX5622
Intervention1 paper4 findingsPubChem 52936034ChEBI 230497
- Animals1
Outcomes
4Ang
downin mice1
1 study
Ang
downin mice1
PLX5622 decreases Ang in mice.
Animalsbrainmales
Microglial depletion triggers distinct molecular responses in male and female aged mouse brains · bioRxiv : the preprint server for biology · 8 Sep 2026 · Preprint
Lzts3
upin mice1
1 study
Lzts3
upin mice1
PLX5622 increases Lzts3 in mice.
Animalsbrainmales
Microglial depletion triggers distinct molecular responses in male and female aged mouse brains · bioRxiv : the preprint server for biology · 8 Sep 2026 · Preprint
miR-223-3p
downin mice1
1 study
miR-223-3p
downin mice1
PLX5622 decreases miR-223-3p in mice.
Animalsbrain
Microglial depletion triggers distinct molecular responses in male and female aged mouse brains · bioRxiv : the preprint server for biology · 8 Sep 2026 · Preprint
miR-146a-5p
downin mice1
1 study
miR-146a-5p
downin mice1
PLX5622 decreases miR-146a-5p in mice.
Animalsbrain
Microglial depletion triggers distinct molecular responses in male and female aged mouse brains · bioRxiv : the preprint server for biology · 8 Sep 2026 · Preprint
Latest
1Microglial depletion triggers distinct molecular responses in male and female aged mouse brains
Aged male mice showed far larger proteomic shifts than females following microglial removal, including alterations in synaptic and mitochondrial proteins.