Kl knockout

Intervention1 paper2 findings

Animals1

Outcomes

2

Sox2

downin mice1

1 study

Kl knockout decreases Sox2 in mice.
Animalstongue epithelium
Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice · Mechanisms of ageing and development · 24 Sep 2026

Taste bud

downin mice1

1 study

Kl knockout decreases taste bud in mice.
Animalstongue epithelium
Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice · Mechanisms of ageing and development · 24 Sep 2026

Latest

1

Animals26 Sep

Reduced SOX2 contributes to taste bud degeneration in accelerated aging mice

Researchers linked lower SOX2 to reduced neurotrophic factors and structural degradation in the tongue tissue of Klotho-deficient mice.

Mechanisms of Ageing and Development · Duong MD et al.