Lmna
GeneMus musculus1 paperMGI 96794NCBI Gene 16905Taxon 10090
- Animals1
Latest
2ApoD drives cellular aging phenotypes through a nuclear mechanotransduction feedback loop
In cultured fibroblasts and mice, apolipoprotein D triggers SUN1 accumulation, reinforcing a signaling cycle that alters gene expression and cellular polarity.
Lactate receptor activation reduces cellular senescence and protects vascular health in mice
Loss of the lactate receptor GPR81 drives arterial senescence and lipid accumulation, while pharmacological stimulation restores vascular homeostasis in progeroid mice.