Chek2
GeneMus musculus1 paper1 findingMGI 1355321NCBI Gene 50883Taxon 10090
- Animals1
Effects
1Chronic inflammation
upin mice1
1 study
Chronic inflammation
upin mice1
Chek2 increases chronic inflammation in mice.
Animalsgranulosa cellfemales
Inhibiting CHK2 improves oocyte quality and reduces ovarian inflammation in aged mice · bioRxiv · 1 Oct 2026 · Preprint
Latest
1Inhibiting CHK2 improves oocyte quality and reduces ovarian inflammation in aged mice
A multi-omic analysis shows that defective luteal resolution and CHK2-driven inflammation drive ovarian aging, but drug inhibition restores oocyte maturation.