Viral pneumonia
Disease1 paper1 finding
- Animals1
Interventions
1Tfam knockdown
upin mice1
1 study
Tfam knockdown
upin mice1
Tfam knockdown increases viral pneumonia in mice.
Animalsinfluenza infectionlung
TFAM deficiency in T cells worsens viral lung pathology and weakens immunity · bioRxiv · 27 Sep 2026 · Preprint
Latest
1TFAM deficiency in T cells worsens viral lung pathology and weakens immunity
Declining TFAM levels impair mitochondrial function in CD8+ T cells, driving tissue damage and weakening long-term immune protection during influenza.