Idiopathic pulmonary fibrosis
Disease3 papers1 findingMeSH D054990
- Animals2
Interventions
1Syringin
downin mice1
1 study
Syringin
downin mice1
Syringin protects against idiopathic pulmonary fibrosis in mice.
Animalsbleomycin-induced pulmonary fibrosislung
Syringin reduces cellular senescence and pulmonary fibrosis in mice and cell models · Chinese journal of natural medicines · 1 Oct 2026
Latest
3AnimalsCellular senescence
Syringin reduces cellular senescence and pulmonary fibrosis in mice and cell models
Computational screening identified the natural compound, which interacts with CHK1 to blunt replication stress and fibrotic signaling.
Rapamycin slows pulmonary fibrosis by reducing lung epithelial cell senescence in mice
The immunosuppressant suppresses epithelial-mesenchymal transition and promotes p53 degradation via the SFN-MDM2 pathway to curb fibrotic lung disease.