Phosphatidylserine
Biomarker1 paper1 finding
- Cells1
Interventions
1Epoxomicin
upin human cells1
1 study
Epoxomicin
upin human cells1
Epoxomicin increases phosphatidylserine in human cells.
“Physiological restoration of proteasome-inhibited RBCs caused accelerated ATP depletion, massive protein aggregation, reduced deformability, hemolysis, and phosphatidylserine exposure”
Cellsduring physiological restorationerythrocyte
Proteasome activity maintains red blood cell integrity during storage and restoration · Antioxidants (Basel, Switzerland) · 9 Sep 2026
Latest
2Model organismsMitochondria
Suppressing clk-1 restores lifespan and mitochondrial function in psd-1 deficient worms
Targeting ubiquinone biosynthesis counteracted reduced oxygen consumption and rescued lifespan loss caused by mitochondrial phosphatidylethanolamine deficiency in Caenorhabditis elegans.
CellsCellular senescence
Proteasome activity maintains red blood cell integrity during storage and restoration
Inhibiting the proteasome accelerates ATP depletion, protein aggregation, and clearance markers in stored and aged red blood cells.