Tert overexpression
Intervention1 paper2 findings
- Cells1
Outcomes
2Pigmentation
downin human cells1
1 study
Pigmentation
downin human cells1
Tert overexpression decreases pigmentation in human cells.
“Melanocyte differentiation and pigmentation programs were generally reduced, particularly in clonal cultures.”
Cellsparticularly in clonal cultureslentiviral vectormelanocyte
Lentiviral hTERT Overexpression Extends the Lifespan of Primary Human Epidermal Melanocytes and Reshapes Transcriptional Programs · Biomolecules · 27 Aug 2026
Lifespan
upin human cells1
1 study
Lifespan
upin human cells1
Tert overexpression extends lifespan in human cells (>10 passages).
“hTERT overexpression extended melanocyte culture lifespan by more than 10 passages.”
Cellslentiviral vectormelanocyte
Lentiviral hTERT Overexpression Extends the Lifespan of Primary Human Epidermal Melanocytes and Reshapes Transcriptional Programs · Biomolecules · 27 Aug 2026