LIN28B knockout
Intervention1 paper1 finding
- Animals1
Outcomes
1Stem cell exhaustion
upin mouse cells1
1 study
Stem cell exhaustion
upin mouse cells1
LIN28B knockout induces stem cell exhaustion in mouse cells.
Cellsfollowing ex vivo expansion cultureshematopoietic stem cell
Fetal gene Lin28b improves ex vivo expansion of aged mouse blood stem cells · Blood · 1 Oct 2026
Latest
1Animals
Fetal gene Lin28b improves ex vivo expansion of aged mouse blood stem cells
Researchers found that boosting Lin28b expression during ex vivo culture restores the transplantation and reconstitution capacity of aged mouse hematopoietic stem cells.