L1HS overexpression
Intervention1 paper1 finding
- Cells1
Outcomes
1Type I interferon signalling
upin human cells1
1 study
Type I interferon signalling
upin human cells1
L1HS overexpression induces type I interferon signalling in human cells.
Cellstransient overexpressionIMR-90
Acute LINE-1 transcription remodels the molecular landscape of human fibroblasts · bioRxiv : the preprint server for biology · 8 Sep 2026 · Preprint
Latest
1CellsPreprint
Acute LINE-1 transcription remodels the molecular landscape of human fibroblasts
Transient overexpression of the retrotransposon alters gene expression, proteins, and secretions while affecting cell cycle and interferon pathways.