Endothelial mitochondria-targeted chemogenetic hydrogen sulfide
Intervention1 paper2 findings
- Animals1
Outcomes
2Age-related pathology
downin mice1
1 study
Age-related pathology
downin mice1
Endothelial mitochondria-targeted chemogenetic hydrogen sulfide decreases age-related pathology in mice.
Animalsremote-control, endothelial-specific, mitochondria-targeted chemogenetic systemblood vessel
Chemogenetic hydrogen sulfide production reverses vascular remodeling in aged mice · bioRxiv · 30 Sep 2026 · Preprint
Cellular senescence
downin mice1
1 study
Cellular senescence
downin mice1
Endothelial mitochondria-targeted chemogenetic hydrogen sulfide decreases cellular senescence in mice.
Animalsremote-control, endothelial-specific, mitochondria-targeted chemogenetic systemendothelial cell
Chemogenetic hydrogen sulfide production reverses vascular remodeling in aged mice · bioRxiv · 30 Sep 2026 · Preprint
Latest
1Chemogenetic hydrogen sulfide production reverses vascular remodeling in aged mice
Targeting hydrogen sulfide generation to endothelial mitochondria mitigated senescence programs and reversed vascular remodeling in aged mice.