hsp-12.6
GeneCaenorhabditis elegans1 paper2 findingsNCBI Gene 177778Taxon 6239
- Model organisms1
Effects
1Physical function
downin worms1
1 study
Physical function
downin worms1
hsp-12.6 protects against physical function in worms.
Model organismsagainst folding or assembly mutations in thick filament proteinsmuscle
Nematode heat-shock protein HSP-12.6 selectively protects muscle thick filaments in vivo · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1 Oct 2026
Associations
1Lifespan
mixedin worms1
1 study
Lifespan
mixedin worms1
hsp-12.6 is associated with lifespan in worms.
Review
Nematode heat-shock protein HSP-12.6 selectively protects muscle thick filaments in vivo · Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 1 Oct 2026
Latest
1Nematode heat-shock protein HSP-12.6 selectively protects muscle thick filaments in vivo
The chaperone regulates lifespan in Caenorhabditis elegans and specifically shields myosin-containing structures without interacting with thin filaments or polyQ aggregates.