Atg5
GeneMus musculus1 paper2 findingsMGI 1277186NCBI Gene 11793Taxon 10090
- Animals1
Effects
2Mortality
downin mice1
1 study
Mortality
downin mice1
Atg5 prevents mortality in mice.
Animalsduring nutrient restriction via Cys19 redox switch
Dietary restriction activates autophagy through selective oxidation of ATG5 · bioRxiv : the preprint server for biology · 24 Sep 2026 · Preprint
Autophagy
is required forin mice1
1 study
Autophagy
is required forin mice1
Atg5 is required for autophagy in mice.
Animalsupon nutrient restriction, via Cys19 oxidation
Dietary restriction activates autophagy through selective oxidation of ATG5 · bioRxiv : the preprint server for biology · 24 Sep 2026 · Preprint
Latest
1Dietary restriction activates autophagy through selective oxidation of ATG5
Reversible oxidation of a single cysteine residue enables core autophagosome formation and prevents severe tissue pathology during nutrient limitation in mice.