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Humans·Preprint
Researchers derived biological age uncertainty across UK Biobank participants, finding that higher uncertainty reflects reduced physiological coherence and predicts worse health outcomes.
medRxiv · 28 Sept · Li Y, Feng G, Yan S et al.
Humans·Preprint
Multi-omics clocks across fourteen organs reveal divergent molecular programs and uncover thirteen candidate genes separating age acceleration from mortality.
Research Square · 30 Sept · Na R, Shi C, Ruan X et al.
Humans·Peer-reviewed
The retinal age gap correlates with mortality, disease risks, and sex-specific genetic pathways in more than 71,000 UK Biobank participants.
Nature communications · 26 Aug · Trofimova O, Böttger L, Bors S et al.
Humans·Peer-reviewed
Cell counts explain less variation in age acceleration and only modestly affect its links to mortality and 176 incident health outcomes.
Genome medicine · 2 Oct · Jonkman TH, Richmond A, BIOS Consortium et al.
Humans·Peer-reviewed
A cross-species single-cell atlas links injured human kidney cells and aged mouse kidneys to shared chromatin reorganization and impaired repair.
Nature aging · 24 Sept · Jeong H, Lake BB, Diep D et al.