Brain agingCells28 Sep 2026

Holdfast-Derived Lipid Extract from the Patagonian Macroalga Macrocystis pyrifera Attenuates Amyloid-β-Induced Neuronal Metabolic Dysfunction In Vitro and Ex Vivo

Pharmaceuticals

Abstract · CC BY

Background : Impaired cerebral glucose metabolism is an early and clinically relevant feature of Alzheimer's disease (AD). Amyloid-β (Aβ) accumulation can further disrupt neuronal energy homeostasis, increasing metabolic and oxidative vulnerability.

The paper

Méndez F, Cisternas P, Ormazabal P et al.

Pharmaceuticals · 18 Sep 2026

doi.org/10.3390/ph19091489 PubMed

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Holdfast-Derived Lipid Extract from the Patagonian Macroalga Macrocystis pyrifera Attenuates Amyloid-β-Induced Neuronal Metabolic Dysfunction In Vitro and Ex Vivo

The paper

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