Reducing ribosome abundance
Intervention1 paper2 findings
- Model organisms1
Outcomes
2Meiotic defects
upin flies1
1 study
Meiotic defects
upin flies1
Reducing ribosome abundance induces meiotic defects in flies.
Model organismsoocytefemales
Declining ribosome function drives reproductive aging in fruit fly and mouse oocytes · bioRxiv · 30 Sep 2026 · Preprint
Developmental competence
downin flies1
1 study
Developmental competence
downin flies1
Reducing ribosome abundance impairs developmental competence in flies.
Model organismsoocytefemales
Declining ribosome function drives reproductive aging in fruit fly and mouse oocytes · bioRxiv · 30 Sep 2026 · Preprint
Latest
1Model organismsPreprint
Declining ribosome function drives reproductive aging in fruit fly and mouse oocytes
A genetic screen and functional assays show that falling translational capacity causes meiotic and developmental defects during oocyte aging.